Endocrine Abstracts

Introduction: Thyrotoxicosis may be associated with anemia (10–34% of thyrotoxic patients), leucopenia (15–30%) and thrombocytopenia (2–5%). We present the case of a 13-year-old girl with Graves’ disease associated with severe pancytopenia.Case presentation: The patient presented with menorrahgia and symptoms suggestive of an upper respiratory tract infection. On examination she was afebrile with a pulse rate of 100/min at rest. She h...

Background: Anabolic androgenic steroids (AAS) are widely used to improve performance and/or enhance appearance. The aim of this study was to assess the impact of AAS on the reproductive system of athletes.Methods: An electronic literature search was conducted, using the databases MEDLINE, CENTRAL, Scopus and Google Scholar. Studies including AAS use in any type, dose, form or duration of intake were included in the review. Main outcomes were AAS effects...

Background: Cladodes of the nopal opuntia streptacantha (prickly-pear cactus) have been traditionally used for the treatment of diabetes in Mexico. Limited data from studies in experimental animals and humans with prediabetes or type 2 diabetes (DM2), have shown promising antihyperglycemic effects using plant extracts of the streptacantha and ficus-indica opuntia species. The purpose of this study was to assess the effect of opuntia ficus-indica<...

Introduction: Obesity is rising worldwide and the number overweight or obese patients with type 1 diabetes mellitus (T1DM) is increased and eating habits (EH) and physical activity (PA) play an important role on glycemic control and weight gain. The aim of the present study was to examine the EH and the exercise level in patients with T1DM and their relation to body weight.Methods: 126 patients with T1DM (55/126 males, 71/126 females) attending our outpa...

Aim: Current guidelines for type 1 diabetes mellitus (DM1) suggest a therapeutic goal for glycosylated hemoglobin (A1c) of < 7.0% in adults and < 7.5% in children and adolescents, while emphasizing the importance of managing dyslipidemia. We aimed to record the achievement of therapeutic goals in DM1 patients followed-up in a Greek tertiary center.Methods: Data were included from DM1 patients who had visited the Department at least once in the pr...

Introduction: Current guidelines emphasize the important role of Continuous Glucose Monitoring (CGM) for type 1 diabetes mellitus (T1DM) management. The aim of the GlucoseML study is the development of a mobile health system for T1DM self-management based on CGM data, physical activity, food intake and insulin dosage. We herein present the development and evaluation of a univariate Autoregressive Moving Average (ARMA) prediction model of interstitial glucose concentration for ...

Background: PCOS is characterized from chronic anovulation, clinically expressed as menstrual irregularities, hyperandrogenism and polycystic ovaries on ultrasound. A growing body of data indicates that PCOS is a life existing disease starting before puberty and lasting post menopause, as hormonal and metabolic changes exist through the life span of the patient. Since the presence of menstrual irregularities constitutes a prerequisite for the diagnosis of PCOS, we wonder if th...

Introduction: Osteoporosis is a prevalent skeletal disease associated with increased fracture risk, morbidity, and mortality. Several meta-analyses have investigated the association between non-genetic, non-pharmacologic factors and osteoporosis risk.Purpose: We aimed to perform an umbrella review of the literature to systematically evaluate the available evidence.Methods: Meta-analyses of observational studies evaluating the assoc...

Introduction: Pheochromocytomas (PCs) and paragangliomas are rare tumours occurring in about 0.6 cases per 100,000 person-years. Biochemically silent PCs with normal catecholamine levels due to lack of catecholamine secretion or subtle secretion within the established normal levels are even rarer. Up to date, biochemically silent PCs are poorly investigated.Aim: To assess the pre-, peri- and post-operative characteristics of patients with biochemically s...